Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004637 | molecular_function | phosphoribosylamine-glycine ligase activity |
| A | 0004641 | molecular_function | phosphoribosylformylglycinamidine cyclo-ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0009113 | biological_process | purine nucleobase biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004637 | molecular_function | phosphoribosylamine-glycine ligase activity |
| B | 0004641 | molecular_function | phosphoribosylformylglycinamidine cyclo-ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| B | 0009113 | biological_process | purine nucleobase biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 601 |
| Chain | Residue |
| B | GLY81 |
| B | GLY84 |
| B | THR97 |
| B | ALA98 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 602 |
| Chain | Residue |
| A | GLY81 |
| A | GLY84 |
| A | ALA98 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 701 |
| Chain | Residue |
| A | GLU75 |
| A | ARG292 |
| A | HOH837 |
| A | ARG13 |
| A | PRO74 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 702 |
| Chain | Residue |
| B | ARG13 |
| B | GLU75 |
| B | ARG292 |
| B | HOH817 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ATP B 501 |
| Chain | Residue |
| B | LYS148 |
| B | VAL160 |
| B | LYS162 |
| B | GLU190 |
| B | GLU191 |
| B | LEU192 |
| B | LEU193 |
| B | GLU197 |
| B | ARG220 |
| B | MET278 |
| B | LEU287 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ATP A 501 |
| Chain | Residue |
| A | VAL160 |
| A | GLU190 |
| A | GLU191 |
| A | LEU193 |
| A | GLU197 |
| A | ARG220 |
| A | ASN229 |
| A | MET278 |
| A | LEU287 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 801 |
| Chain | Residue |
| B | PRO211 |
| B | PRO213 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 802 |
| Chain | Residue |
| B | TYR344 |
| B | GLY384 |
| B | ARG385 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 803 |
| Chain | Residue |
| A | HIS25 |
| A | VAL27 |
| A | LYS44 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 804 |
| Chain | Residue |
| A | TYR344 |
| A | GLY384 |
| A | ARG385 |
| A | HOH834 |
Functional Information from PROSITE/UniProt
| site_id | PS00184 |
| Number of Residues | 8 |
| Details | GARS Phosphoribosylglycinamide synthetase signature. RFGDPEcQ |
| Chain | Residue | Details |
| A | ARG292-GLN299 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU190 | |
| A | GLU197 | |
| A | ARG220 | |
| A | ASN229 | |
| B | GLU190 | |
| B | GLU197 | |
| B | ARG220 | |
| B | ASN229 | |
| Chain | Residue | Details |
| A | GLU288 | |
| A | ASN290 | |
| B | GLU288 | |
| B | ASN290 | |
| Chain | Residue | Details |
| A | ALA2 | |
| B | ALA2 | |
| Chain | Residue | Details |
| A | SER10 | |
| B | SER10 | |
| Chain | Residue | Details |
| A | LYS350 | |
| B | LYS350 | |
