2QE5

Structure of HCV NS5B Bound to an Anthranilic Acid Inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	RNA-directed RNA polymerase	polymer	578	64247.6	4	UniProt (Q99AU2) Pfam (PF00998)	Hepatitis C virus subtype 1b	NS5B, p68
2	E (A)	2-{[(4-CHLOROPHENOXY)ACETYL]AMINO}BENZOIC ACID	non-polymer		305.7	1	Chemie (617)
3	F (A)	water	water		18.0	6	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 570 (UniProt: Q99AU2)

PDB	External Database	Details
Gly 571	-	expression tag
Ser 572	-	expression tag
His 573	-	expression tag
His 574	-	expression tag
His 575	-	expression tag
His 576	-	expression tag
His 577	-	expression tag
His 578	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	256990.4
Non-Polymers*	Number of molecules	1
	Total formula weight	305.7
All*	Total formula weight	257296.1

*Water molecules are not included.