2Q9Q

The crystal structure of full length human GINS complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	DNA replication complex GINS protein PSF2	polymer	191	21979.3	2	UniProt (Q9Y248) Pfam (PF05916)	Homo sapiens (human)
2	B, F (B, F)	GINS complex subunit 4	polymer	223	26081.9	2	UniProt (Q9BRT9) Pfam (PF05916) Pfam (PF16922)	Homo sapiens (human)
3	C, G (C, G)	DNA replication complex GINS protein PSF1	polymer	196	23036.5	2	UniProt (Q14691) Pfam (PF05916)	Homo sapiens (human)
4	D, H (D, H)	GINS complex subunit 3	polymer	220	24756.7	2	UniProt (Q9BRX5) Pfam (PF22466) Pfam (PF05916)	Homo sapiens (human)	Psf3 homolog
5	I, J, K, L, M... (A, B, C, D, E...)	water	water		18.0	453	Chemie (HOH)

Sequence modifications

A, E: 1 - 185 (UniProt: Q9Y248)

PDB	External Database	Details
Gly -5	-	cloning artifact
Pro -4	-	cloning artifact
Leu -3	-	cloning artifact
Gly -2	-	cloning artifact
Ser -1	-	cloning artifact
Asn 0	-	cloning artifact

C, G: 1 - 196 (UniProt: Q14691)

PDB	External Database	Details
Ile 97	Val 97	variant

D, H: 2 - 216 (UniProt: Q9BRX5)

PDB	External Database	Details
Gly -3	-	cloning artifact
Pro -2	-	cloning artifact
Gly -1	-	cloning artifact
Gly 0	-	cloning artifact
Gly 1	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	191708.8
All*	Total formula weight	191708.8

*Water molecules are not included.