2Q8E
Specificity and Mechanism of JMJD2A, a Trimethyllysine-Specific Histone Demethylase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | JmjC domain-containing histone demethylation protein 3A | polymer | 352 | 40863.5 | 2 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) In PDB | Homo sapiens (human) | Jumonji domain-containing protein 2A |
| 2 | F, G | histone 3 peptide | polymer | 16 | 1801.1 | 2 | |||
| 3 | A, B | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 4 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | A, B | N-OXALYLGLYCINE | non-polymer | 147.1 | 2 | Chemie (OGA) | |||
| 6 | water | water | 18.0 | 290 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 350 (UniProt: O75164)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 85329.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 542.4 | |
| All* | Total formula weight | 85871.7 |
