2Q7D
Crystal Structure of Human Inositol 1,3,4-Trisphosphate 5/6-kinase (ITPK1) in complex with AMPPNP and Mn2+
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Inositol-tetrakisphosphate 1-kinase | polymer | 346 | 39031.3 | 2 | UniProt (Q13572) Pfam (PF17927) Pfam (PF05770) In PDB | Homo sapiens (human) | Inositol- triphosphate 5/6-kinase, Inositol 1,3,4-trisphosphate 5/6-kinase, Ins1,3,4, P3, 5/6-kinase |
2 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
4 | A, B | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
5 | water | water | 18.0 | 709 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 335 (UniProt: Q13572)
PDB | External Database | Details |
---|---|---|
Gly -10 | - | expression tag |
Ser -9 | - | expression tag |
Asp -8 | - | expression tag |
Lys -7 | - | expression tag |
Ile -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 78062.7 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 2384.9 | |
All* | Total formula weight | 80447.6 |