2PD6
Structure of human hydroxysteroid dehydrogenase type 8, HSD17B8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Estradiol 17-beta-dehydrogenase 8 | polymer | 264 | 27466.2 | 4 | UniProt (Q92506) Pfam (PF13561) | Homo sapiens (human) | 17-beta-HSD 8, 17- beta-hydroxysteroid dehydrogenase 8, Protein Ke6, Ke-6 |
| 2 | E, F, G, H (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 207 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 6 - 261 (UniProt: Q92506)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | cloning artifact |
| Ala 262 | - | cloning artifact |
| Glu 263 | - | cloning artifact |
| Asn 264 | - | cloning artifact |
| Leu 265 | - | cloning artifact |
| Tyr 266 | - | cloning artifact |
| Phe 267 | - | cloning artifact |
| Gln 268 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 109864.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2653.7 | |
| All* | Total formula weight | 112518.6 |
