2PBI
The multifunctional nature of Gbeta5/RGS9 revealed from its crystal structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Regulator of G-protein signaling 9 | polymer | 424 | 49940.2 | 2 | UniProt (A1L352) Pfam (PF00610) Pfam (PF18148) Pfam (PF00631) Pfam (PF00615) UniProt (by SIFTS) (O54828) | Mus musculus (house mouse) | |
| 2 | B, D (B, D) | Guanine nucleotide-binding protein subunit beta 5 | polymer | 354 | 38835.7 | 2 | UniProt (P62881) Pfam (PF00400) | Mus musculus (house mouse) | Transducin beta chain 5, Gbeta5 |
| 3 | E, F, G, H, I... (A, B, C, D) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 4 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 890 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 422 (UniProt: A1L352)
B, D: 1 - 353 (UniProt: P62881)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 177551.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 828.8 | |
| All* | Total formula weight | 178380.5 |
