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2OZO

Autoinhibited intact human ZAP-70

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein kinase ZAP-70polymer61369348.71UniProt (P43403)
Pfam (PF00017)
Pfam (PF07714)
Homo sapiens (human)70 kDa zeta-associated protein, Syk-related tyrosine kinase
2B
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
3C
(A)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
4D
(A)
waterwater18.069Chemie (HOH)
Sequence modifications
A: 1 - 606 (UniProt: P43403)
PDBExternal DatabaseDetails
Phe 315Tyr 315engineered mutation
Phe 319Tyr 319engineered mutation
Asn 461Asp 461engineered mutation
Gly 607-cloning artifact
Ser 608-cloning artifact
Ala 609-cloning artifact
Leu 610-cloning artifact
Glu 611-cloning artifact
Val 612-cloning artifact
Ala 613-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight69348.7
Non-Polymers*Number of molecules2
Total formula weight530.5
All*Total formula weight69879.2
*Water molecules are not included.

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PDB entries from 2025-07-02

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