2OZO
Autoinhibited intact human ZAP-70
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Tyrosine-protein kinase ZAP-70 | polymer | 613 | 69348.7 | 1 | UniProt (P43403) Pfam (PF00017) Pfam (PF07714) | Homo sapiens (human) | 70 kDa zeta-associated protein, Syk-related tyrosine kinase |
2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
3 | C (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
4 | D (A) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A: 1 - 606 (UniProt: P43403)
PDB | External Database | Details |
---|---|---|
Phe 315 | Tyr 315 | engineered mutation |
Phe 319 | Tyr 319 | engineered mutation |
Asn 461 | Asp 461 | engineered mutation |
Gly 607 | - | cloning artifact |
Ser 608 | - | cloning artifact |
Ala 609 | - | cloning artifact |
Leu 610 | - | cloning artifact |
Glu 611 | - | cloning artifact |
Val 612 | - | cloning artifact |
Ala 613 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 69348.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 530.5 | |
All* | Total formula weight | 69879.2 |