2OZA

Structure of p38alpha complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	MAP kinase-activated protein kinase 2	polymer	356	40983.5	1	UniProt (P49137) Pfam (PF00069)	Homo sapiens (human)	MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAPK-2; MK2
2	B (B)	Mitogen-activated protein kinase 14	polymer	366	42100.0	1	UniProt (P47811) Pfam (PF00069)	Mus musculus (house mouse)	Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; CRK1
3	C, D (A, B)	water	water		18.0	60	Chemie (HOH)

Sequence modifications

A: 47 - 400 (UniProt: P49137)

PDB	External Database	Details
Gly 45	-	insertion
Ser 46	-	insertion

B: 2 - 360 (UniProt: P47811)

PDB	External Database	Details
Met -5	-	insertion
Ala -4	-	insertion
His -3	-	insertion
His -2	-	insertion
His -1	-	insertion
His 0	-	insertion
His 1	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83083.4
All*	Total formula weight	83083.4

*Water molecules are not included.