2OAX
Crystal structure of the S810L mutant mineralocorticoid receptor associated with SC9420
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Mineralocorticoid receptor | polymer | 256 | 29701.4 | 6 | UniProt (P08235) Pfam (PF00104) | Homo sapiens (human) | MR |
| 2 | G, H, I, J, K... (A, B, C, D, E...) | SPIRONOLACTONE | non-polymer | 416.6 | 6 | Chemie (SNL) PubChem (16757735) PubChem (18594034) PubChem (5267) PubChem (16394537) PubChem (24867532) PubChem (24884066) PubChem (44268286) PubChem (44280002) PubChem (1742267) PubChem (1742266) PubChem (50937095) PubChem (941624) PubChem (53316433) PubChem (54670637) PubChem (58649021) PubChem (59078570) PubChem (59106600) PubChem (53485777) PubChem (60108251) PubChem (60113353) PubChem (59105084) PubChem (6093165) PubChem (73896881) PubChem (6419955) PubChem (6432512) PubChem (76974557) PubChem (5833) PubChem (6604008) PubChem (6604182) PubChem (89555390) PubChem (6710654) PubChem (7061088) PubChem (7061090) PubChem (90660429) PubChem (10477021) PubChem (1255733) PubChem (11509929) PubChem (1425524) PubChem (11863525) PubChem (11869418) PubChem (11869419) PubChem (11869420) PubChem (11869578) PubChem (11869580) PubChem (11957686) PubChem (12358364) PubChem (100923457) PubChem (117072388) PubChem (7058140) PubChem (124303478) PubChem (124304402) PubChem (124900200) PubChem (129010254) PubChem (11869579) PubChem (122680945) PubChem (124304445) PubChem (124746581) PubChem (124900199) PubChem (129009897) PubChem (138756141) PubChem (131698401) PubChem (139421976) PubChem (154731467) | |||
| 3 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 339 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 731 - 984 (UniProt: P08235)
| PDB | External Database | Details |
|---|---|---|
| Gly 729 | - | expression tag |
| Ser 730 | - | expression tag |
| Leu 810 | Ser 810 | engineered mutation |
| Ala 910 | Cys 910 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 178208.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2499.4 | |
| All* | Total formula weight | 180707.9 |
