2OAX
Crystal structure of the S810L mutant mineralocorticoid receptor associated with SC9420
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Mineralocorticoid receptor | polymer | 256 | 29701.4 | 6 | UniProt (P08235) Pfam (PF00104) | Homo sapiens (human) | MR |
| 2 | G, H, I, J, K... (A, B, C, D, E...) | SPIRONOLACTONE | non-polymer | 416.6 | 6 | Chemie (SNL) | |||
| 3 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 339 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 731 - 984 (UniProt: P08235)
| PDB | External Database | Details |
|---|---|---|
| Gly 729 | - | expression tag |
| Ser 730 | - | expression tag |
| Leu 810 | Ser 810 | engineered mutation |
| Ala 910 | Cys 910 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 178208.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2499.4 | |
| All* | Total formula weight | 180707.9 |
