2O3E
Crystal structure of engineered neurolysin with thimet oligopeptidase specificity for neurotensin cleavage site.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neurolysin | polymer | 678 | 77644.6 | 1 | UniProt (P42676) Pfam (PF01432) | Rattus norvegicus (Norway rat) | Neurotensin endopeptidase, Mitochondrial oligopeptidase M, Microsomal endopeptidase, MEP |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence modifications
A: 1 - 678 (UniProt: P42676)
| PDB | External Database | Details |
|---|---|---|
| Glu 470 | Arg 493 | engineered mutation |
| Arg 499 | Thr 522 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 77644.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 77710.1 |
