2O1S

1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Escherichia coli

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	1-deoxy-D-xylulose-5-phosphate synthase	polymer	621	68797.8	4	UniProt (P77488) Pfam (PF13292) Pfam (PF02779) Pfam (PF02780) In PDB	Escherichia coli	1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS
2	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	A, B, C, D	POTASSIUM ION	non-polymer		39.1	4	Chemie (K)
4	A, C	THIAMINE DIPHOSPHATE	non-polymer		425.3	2	Chemie (TPP)
5	B, D	DIPHOSPHATE	non-polymer		173.9	2	Chemie (DPO)
6		water	water		18.0	658	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 620 (UniProt: P77488)

PDB	External Database	Details
Mse 1	Met 0	modified residue
Mse 159	Met 158	modified residue
Mse 164	Met 163	modified residue
Mse 174	Met 173	modified residue
Mse 183	Met 182	modified residue
Mse 236	Met 235	modified residue
Mse 269	Met 268	modified residue
Mse 281	Met 280	modified residue
Mse 340	Met 339	modified residue
Mse 346	Met 345	modified residue
Mse 352	Met 351	modified residue
Mse 446	Met 445	modified residue
Mse 449	Met 448	modified residue
Mse 460	Met 459	modified residue
Mse 515	Met 514	modified residue
Mse 532	Met 531	modified residue
Mse 546	Met 545	modified residue
Mse 562	Met 561	modified residue
Mse 574	Met 573	modified residue
Mse 600	Met 599	modified residue
Mse 611	Met 610	modified residue
Leu 621	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	275191.2
Non-Polymers*	Number of molecules	12
	Total formula weight	1452.1
All*	Total formula weight	276643.3

*Water molecules are not included.