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2NYR

Crystal Structure of Human Sirtuin Homolog 5 in Complex with Suramin

Replaces:  2FZQ
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BNAD-dependent deacetylase sirtuin-5polymer27129426.52UniProt (Q9NXA8)
Pfam (PF02146)
In PDB
Homo sapiens (human)SIR2-like protein 5
2A, BZINC IONnon-polymer65.42Chemie (ZN)
3B8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACIDnon-polymer1297.31Chemie (SVR)
4waterwater18.0253Chemie (HOH)
Sequence modifications
A, B: 34 - 302 (UniProt: Q9NXA8)
PDBExternal DatabaseDetails
Gly 32-expression tag
Ser 33-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight58853.0
Non-Polymers*Number of molecules3
Total formula weight1428.1
All*Total formula weight60281.1
*Water molecules are not included.

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PDB entries from 2024-04-24

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