Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0036054 | molecular_function | protein-malonyllysine demalonylase activity |
| A | 0036055 | molecular_function | protein-succinyllysine desuccinylase activity |
| A | 0070403 | molecular_function | NAD+ binding |
| B | 0036054 | molecular_function | protein-malonyllysine demalonylase activity |
| B | 0036055 | molecular_function | protein-succinyllysine desuccinylase activity |
| B | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 46 |
| Details | BINDING SITE FOR RESIDUE SVR B 401 |
| Chain | Residue |
| A | ALA59 |
| A | ARG105 |
| A | ASN141 |
| A | ILE142 |
| A | PHE223 |
| A | ASN226 |
| A | LEU232 |
| A | TYR255 |
| A | MET259 |
| A | HOH573 |
| A | HOH575 |
| A | PRO68 |
| A | HOH616 |
| B | PHE70 |
| B | ARG71 |
| B | ALA82 |
| B | ALA86 |
| B | TYR102 |
| B | ARG105 |
| B | GLN140 |
| B | ILE142 |
| B | HIS158 |
| A | THR69 |
| B | VAL220 |
| B | VAL221 |
| B | PHE223 |
| B | GLY224 |
| B | GLU225 |
| B | ASN226 |
| B | LEU232 |
| B | VAL254 |
| B | TYR255 |
| B | MET259 |
| A | PHE70 |
| B | HOH503 |
| B | HOH508 |
| B | HOH557 |
| B | HOH559 |
| B | HOH561 |
| B | HOH562 |
| B | HOH584 |
| A | ARG71 |
| A | ALA82 |
| A | ALA86 |
| A | PHE101 |
| A | TYR102 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 501 |
| Chain | Residue |
| A | CYS166 |
| A | CYS169 |
| A | CYS207 |
| A | CYS212 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 501 |
| Chain | Residue |
| B | CYS166 |
| B | CYS169 |
| B | CYS207 |
| B | CYS212 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00236","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22076378","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29180469","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 52 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03160","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22076378","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22767592","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2006","submissionDatabase":"PDB data bank","title":"Crystal structure of human sirtuin homolog 5 in complex with NAD.","authoringGroup":["Structural genomics consortium (SGC)"]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03160","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
