2NS7

How an in vitro selected peptide mimics the antibiotic tetracycline to induce TET repressor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Tetracycline repressor protein	polymer	208	23531.7	4	UniProt (P04483) UniProt (P0ACT4) Pfam (PF00440) Pfam (PF02909)	Escherichia coli

Sequence modifications

A, B, C, D: 1 - 187 (UniProt: P04483)

PDB	External Database	Details
Ser 68	Cys 68	engineered mutation
Asn 88	Cys 88	engineered mutation
Thr 121	Cys 121	engineered mutation
Ser 144	Cys 144	engineered mutation

A, B, C, D: 188 - 208 (UniProt: P0ACT4)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	94126.6
All*	Total formula weight	94126.6

*Water molecules are not included.