2NRU
Crystal structure of IRAK-4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Interleukin-1 receptor-associated kinase 4 | polymer | 307 | 34578.0 | 4 | UniProt (Q9NWZ3) Pfam (PF07714) In PDB | Homo sapiens (human) | IRAK-4, NY- REN-64 antigen |
| 2 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | A, B, C, D | 1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE | non-polymer | 440.4 | 4 | Chemie (T12) | |||
| 4 | water | water | 18.0 | 483 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 154 - 460 (UniProt: Q9NWZ3)
| PDB | External Database | Details |
|---|---|---|
| Tpo 345 | Thr 345 | modified residue |
| Sep 346 | Ser 346 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 138311.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1953.9 | |
| All* | Total formula weight | 140265.8 |
