2MEJ
Solution Structure of the Complex Between BCL-xL and the p53 Core Domain determined with PRE restraints
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bcl-2-like protein 1 | polymer | 212 | 23669.9 | 1 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) | Homo sapiens (human) | Bcl2-L-1, Apoptosis regulator Bcl-X |
| 2 | B (B) | Cellular tumor antigen p53 | polymer | 217 | 24412.7 | 1 | UniProt (P04637) Pfam (PF00870) | Homo sapiens (human) | Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53 |
| 3 | C (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A: 4 - 212 (UniProt: Q07817)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| His 2 | - | expression tag |
| Ser 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48082.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 48148.1 |
