2LKX

NMR structure of the homeodomain of Pitx2 in complex with a TAATCC DNA binding site

Replaces:  1YZ8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Pituitary homeobox 3	polymer	68	8486.5	1	UniProt (O75364) Pfam (PF00046) UniProt (by SIFTS) (Q99697) In PDB	Homo sapiens (human)	Homeobox protein PITX3, Paired-like homeodomain transcription factor 3
2	B	DNA (5'-D(*GP*CP*TP*CP*TP*AP*AP*TP*CP*CP*CP*CP*G)-3')	polymer	13	3887.5	1
3	C	DNA (5'-D(*CP*GP*GP*GP*GP*AP*TP*TP*AP*GP*AP*GP*C)-3')	polymer	13	4056.6	1

Sequence modifications

A: 1 - 60 (UniProt: O75364)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
Glu 61	-	expression tag
Phe 62	-	expression tag
Ile 63	-	expression tag
Val 64	-	expression tag
Thr 65	-	expression tag
Asp 66	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	16430.7
All*	Total formula weight	16430.7

*Water molecules are not included.