2LI8
The solution structure of the Lin28-ZnF domains bound to AGGAGAU of pre-let-7 miRNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein lin-28 homolog A | polymer | 74 | 8033.4 | 1 | UniProt (Q9H9Z2) Pfam (PF00098) Pfam (PF21890) | Homo sapiens (human) | Lin-28A, Zinc finger CCHC domain-containing protein 1 |
| 2 | B (B) | RNA (5'-R(*AP*GP*GP*AP*GP*AP*U)-3') | polymer | 7 | 2284.4 | 1 | |||
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A: 124 - 186 (UniProt: Q9H9Z2)
| PDB | External Database | Details |
|---|---|---|
| Ser 113 | - | expression tag |
| Ser 114 | - | expression tag |
| Gly 115 | - | expression tag |
| Leu 116 | - | expression tag |
| Val 117 | - | expression tag |
| Pro 118 | - | expression tag |
| Arg 119 | - | expression tag |
| Gly 120 | - | expression tag |
| Ser 121 | - | expression tag |
| His 122 | - | expression tag |
| Met 123 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 10317.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 10448.6 |
