2LI8

The solution structure of the Lin28-ZnF domains bound to AGGAGAU of pre-let-7 miRNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein lin-28 homolog A	polymer	74	8033.4	1	UniProt (Q9H9Z2) Pfam (PF00098) In PDB	Homo sapiens (human)	Lin-28A, Zinc finger CCHC domain-containing protein 1
2	B	RNA (5'-R(*AP*GP*GP*AP*GP*AP*U)-3')	polymer	7	2284.4	1
3	A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A: 124 - 186 (UniProt: Q9H9Z2)

PDB	External Database	Details
Ser 113	-	expression tag
Ser 114	-	expression tag
Gly 115	-	expression tag
Leu 116	-	expression tag
Val 117	-	expression tag
Pro 118	-	expression tag
Arg 119	-	expression tag
Gly 120	-	expression tag
Ser 121	-	expression tag
His 122	-	expression tag
Met 123	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	10317.8
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	10448.6

*Water molecules are not included.