2LI8

The solution structure of the Lin28-ZnF domains bound to AGGAGAU of pre-let-7 miRNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 187

Chain	Residue
A	CYS139
A	CYS142
A	HIS147
A	CYS152

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 188

Chain	Residue
A	CYS161
A	CYS164
A	HIS169
A	CYS174

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	17
Details	Zinc finger: {"description":"CCHC-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00047","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	17
Details	Zinc finger: {"description":"CCHC-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00047","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---