2JU4
NMR structure of the gamma subunit of cGMP phosphodiesterase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | polymer | 87 | 9472.1 | 1 | UniProt (P04972) Pfam (PF04868) In PDB | Bos taurus (cattle) | GMP-PDE gamma |
| 2 | A | (3'R)-1'-oxyl-2',2',5',5'-tetramethyl-1,3'-bipyrrolidine-2,5-dione | non-polymer | 239.3 | 10 | Chemie (RCY) |
Sequence modifications
A: 1 - 87 (UniProt: P04972)
| PDB | External Database | Details |
|---|---|---|
| Cys 10 | Phe 10 | engineered mutation |
| Cys 21 | Val 21 | engineered mutation |
| Cys 30 | Phe 30 | engineered mutation |
| Cys 38 | Phe 38 | engineered mutation |
| Cys 50 | Phe 50 | engineered mutation |
| Cys 60 | Leu 60 | engineered mutation |
| Cys 73 | Phe 73 | engineered mutation |
| Cys 76 | Leu 76 | engineered mutation |
| Cys 87 | Ile 87 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 9472.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2392.9 | |
| All* | Total formula weight | 11865.0 |
