2JM6

Solution structure of MCL-1 complexed with NOXAB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Noxa	polymer	27	3144.7	1	UniProt (Q9JM54) Pfam (PF15150)	Mus musculus (house mouse)
2	B (B)	Myeloid cell leukemia-1 protein Mcl-1 homolog	polymer	162	18260.7	1	UniProt (P97287) Pfam (PF00452)	Mus musculus (house mouse)	Bcl-2-related protein EAT/mcl1, Induced myeloid leukemia cell differentiation protein

Sequence modifications

A: 68 - 93 (UniProt: Q9JM54)

PDB	External Database	Details
Met 94	-	expression tag

B: 152 - 308 (UniProt: P97287)

PDB	External Database	Details
Gly 147	-	expression tag
Pro 148	-	expression tag
Leu 149	-	expression tag
Gly 150	-	expression tag
Ser 151	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	21405.4
All*	Total formula weight	21405.4

*Water molecules are not included.