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2JM6

Solution structure of MCL-1 complexed with NOXAB

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ANoxapolymer273144.71UniProt (Q9JM54)
Pfam (PF15150)
In PDB
Mus musculus (house mouse)
2BMyeloid cell leukemia-1 protein Mcl-1 homologpolymer16218260.71UniProt (P97287)
Pfam (PF00452)
In PDB
Mus musculus (house mouse)Bcl-2-related protein EAT/mcl1, Induced myeloid leukemia cell differentiation protein
Sequence modifications
A: 68 - 93 (UniProt: Q9JM54)
PDBExternal DatabaseDetails
Met 94-expression tag
B: 152 - 308 (UniProt: P97287)
PDBExternal DatabaseDetails
Gly 147-expression tag
Pro 148-expression tag
Leu 149-expression tag
Gly 150-expression tag
Ser 151-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight21405.4
All*Total formula weight21405.4
*Water molecules are not included.

224572

PDB entries from 2024-09-04

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