2JLR

Dengue virus 4 NS3 helicase in complex with AMPPNP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	SERINE PROTEASE SUBUNIT NS3	polymer	451	51353.5	1	UniProt (Q2YHF0) Pfam (PF07652) Pfam (PF20907)	DENGUE VIRUS 4	DENV4 NS3 HELICASE, NON-STRUCTURAL PROTEIN 3
2	B (A)	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
3	C (A)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)
4	D (A)	water	water		18.0	311	Chemie (HOH)

Sequence modifications

A: 168 - 171 (PDB: 2JLR)
A: 172 - 618 (UniProt: Q2YHF0)

PDB	External Database	Details
Asp 250	Glu 1724	conflict
Cys 292	Ser 1766	conflict
Ser 321	Thr 1795	conflict
Arg 381	Lys 1855	conflict
Lys 526	Arg 2000	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	51353.5
Non-Polymers*	Number of molecules	2
	Total formula weight	561.1
All*	Total formula weight	51914.6

*Water molecules are not included.