2JHT

CRYSTAL STRUCTURE OF RHOGDI K135T,K138T,K141T MUTANT

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	RHO GDP-DISSOCIATION INHIBITOR 1	polymer	138	15711.8	4	UniProt (P52565) Pfam (PF02115)	HOMO SAPIENS (HUMAN)	RHO GDI 1, RHO-GDI ALPHA
2	E, G (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	F (A)	LITHIUM ION	non-polymer		6.9	1	Chemie (LI)
4	H, I, J, K (A, B, C, D)	water	water		18.0	257	Chemie (HOH)

Sequence modifications

A, B, C, D: 65 - 66 (PDB: 2JHT)
A, B, C, D: 67 - 202 (UniProt: P52565)

PDB	External Database	Details
Thr 135	Lys 134	engineered mutation
Thr 138	Lys 137	engineered mutation
Thr 141	Lys 140	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	62847.3
Non-Polymers*	Number of molecules	3
	Total formula weight	199.1
All*	Total formula weight	63046.3

*Water molecules are not included.