2JHT
CRYSTAL STRUCTURE OF RHOGDI K135T,K138T,K141T MUTANT
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005094 | molecular_function | Rho GDP-dissociation inhibitor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0007266 | biological_process | Rho protein signal transduction |
| B | 0005094 | molecular_function | Rho GDP-dissociation inhibitor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0007266 | biological_process | Rho protein signal transduction |
| C | 0005094 | molecular_function | Rho GDP-dissociation inhibitor activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0007266 | biological_process | Rho protein signal transduction |
| D | 0005094 | molecular_function | Rho GDP-dissociation inhibitor activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0007266 | biological_process | Rho protein signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A1203 |
| Chain | Residue |
| A | LYS199 |
| A | LYS200 |
| A | ASP201 |
| A | HOH2100 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE LI A1204 |
| Chain | Residue |
| D | SER148 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B1203 |
| Chain | Residue |
| B | HOH2054 |
| B | HOH2055 |
| B | HOH2056 |
| B | HOH2057 |
| A | MET145 |
| B | ARG152 |
| B | ALA153 |
| B | GLU154 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | GLU106 | |
| D | GLU106 | |
| D | TYR128 | |
| D | SER179 | |
| A | TYR128 | |
| A | SER179 | |
| B | GLU106 | |
| B | TYR128 | |
| B | SER179 | |
| C | GLU106 | |
| C | TYR128 | |
| C | SER179 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q99PT1 |
| Chain | Residue | Details |
| A | THR142 | |
| B | THR142 | |
| C | THR142 | |
| D | THR142 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25114211 |
| Chain | Residue | Details |
| A | ILE139 | |
| D | ILE139 | |
| D | THR142 | |
| A | THR142 | |
| B | ILE139 | |
| B | THR142 | |
| C | ILE139 | |
| C | THR142 |
