2J59

Crystal structure of the ARF1:ARHGAP21-ArfBD complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	ADP-RIBOSYLATION FACTOR 1	polymer	166	18951.6	6	UniProt (P84078) Pfam (PF00025) In PDB	MUS MUSCULUS (MOUSE)	ARF1
2	M, N, O, P, Q...	RHO-GTPASE ACTIVATING PROTEIN 10	polymer	168	19378.9	6	UniProt (Q8NI19) Pfam (PF00169) UniProt (by SIFTS) (Q5T5U3) In PDB	HOMO SAPIENS (HUMAN)	RHOGAP PROTEIN, ARHGAP21
3	F, A, B, C, D...	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	6	Chemie (GTP)
4	F, A, B, C, D...	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
5	F, A, B	1,4-DIETHYLENE DIOXIDE	non-polymer		88.1	3	Chemie (DIO)
6	O, C, E	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
7	M, N, O, P, Q...	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
8		water	water		18.0	1656	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 16 - 17 (PDB: 2J59)
A, B, C, D, E, F: 18 - 181 (UniProt: P84078)

PDB	External Database	Details
Leu 71	Gln 70	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	229983.2
Non-Polymers*	Number of molecules	24
	Total formula weight	4311.8
All*	Total formula weight	234295.0

*Water molecules are not included.