2J0U
The crystal structure of eIF4AIII-Barentsz complex at 3.0 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATP-DEPENDENT RNA HELICASE DDX48 | polymer | 374 | 42793.3 | 1 | UniProt (P38919) Pfam (PF00270) Pfam (PF00271) | HOMO SAPIENS (HUMAN) | EIF4AIII RNA-HELICASE, DEAD BOX PROTEIN 48, EUKARYOTIC INITIATION FACTOR 4A-LIKE NUK-34, NUCLEAR MATRIX PROTEIN 265, HNMP 265, EUKARYOTIC TRANSLATION INITIATION FACTOR 4A ISOFORM 3 |
| 2 | B (B) | ATP-DEPENDENT RNA HELICASE DDX48 | polymer | 374 | 42763.2 | 1 | UniProt (P38919) Pfam (PF00270) Pfam (PF00271) | HOMO SAPIENS (HUMAN) | EIF4AIII RNA-HELICASE, DEAD BOX PROTEIN 48, EUKARYOTIC INITIATION FACTOR 4A-LIKE NUK-34, NUCLEAR MATRIX PROTEIN 265, HNMP 265, EUKARYOTIC TRANSLATION INITIATION FACTOR 4A ISOFORM 3 |
| 3 | C (T) | PROTEIN CASC3 | polymer | 114 | 13356.6 | 1 | UniProt (O15234) Pfam (PF09405) | HOMO SAPIENS (HUMAN) | BARENTSZ, CANCER SUSCEPTIBILITY CANDIDATE GENE 3 PROTEIN, METASTATIC LYMPH NODE PROTEIN 51, MLN 51 PROTEIN, BARENTSZ PROTEIN, BTZ |
Sequence modifications
A: 38 - 411 (UniProt: P38919)
B: 38 - 411 (UniProt: P38919)
| PDB | External Database | Details |
|---|---|---|
| Val 94 | Ile 93 | conflict |
| Val 122 | Ile 121 | conflict |
| Val 378 | Ile 377 | conflict |
| Val 388 | Ile 387 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Val 94 | Ile 93 | conflict |
| Val 122 | Ile 121 | conflict |
| Ser 137 | Cys 136 | conflict |
| Val 225 | Ile 224 | conflict |
| Val 378 | Ile 377 | conflict |
| Val 388 | Ile 387 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 98913.1 | |
| All* | Total formula weight | 98913.1 |
