2IYF
The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | OLEANDOMYCIN GLYCOSYLTRANSFERASE | polymer | 415 | 45392.0 | 2 | UniProt (Q3HTL6) UniProt (by SIFTS) (Q53685) | STREPTOMYCES ANTIBIOTICUS | OLED |
| 2 | C, E (A, B) | ERYTHROMYCIN A | non-polymer | 733.9 | 2 | Chemie (ERY) PubChem (16219331) PubChem (16757675) PubChem (12560) PubChem (22489166) PubChem (22836457) PubChem (22836628) PubChem (23229191) PubChem (24797108) PubChem (16219337) PubChem (16401342) PubChem (16759276) PubChem (18397931) PubChem (18528813) PubChem (21550772) PubChem (22836626) PubChem (44451949) PubChem (45107170) PubChem (45107190) PubChem (45107269) PubChem (45107273) PubChem (44317775) PubChem (44547821) PubChem (44563509) PubChem (49867933) PubChem (51066560) PubChem (45107581) PubChem (53384904) PubChem (53384913) PubChem (57358551) PubChem (50987679) PubChem (57587180) PubChem (53393685) PubChem (54359201) PubChem (59974395) PubChem (60044171) PubChem (60086513) PubChem (57357418) PubChem (66577477) PubChem (57893297) PubChem (58594795) PubChem (58593559) PubChem (59022390) PubChem (59062422) PubChem (59064284) PubChem (59093569) PubChem (59284311) PubChem (59511080) PubChem (59897430) PubChem (59903654) PubChem (60009793) PubChem (60024420) PubChem (66639443) PubChem (66899541) PubChem (71024089) PubChem (177390461) PubChem (177679009) PubChem (6364614) PubChem (3255) PubChem (8233) PubChem (9361) PubChem (6604684) PubChem (6713919) PubChem (154401) PubChem (89970519) PubChem (70897564) PubChem (71306958) PubChem (90472408) PubChem (73265320) PubChem (73456721) PubChem (73946784) PubChem (456593) PubChem (467795) PubChem (489009) PubChem (10034134) PubChem (86820632) PubChem (90473776) PubChem (90746906) PubChem (12358509) PubChem (12358517) PubChem (12966969) PubChem (97293607) PubChem (91434318) PubChem (91558259) PubChem (15986867) PubChem (99719272) PubChem (97293608) PubChem (99719271) PubChem (110189186) PubChem (6540620) PubChem (6602506) PubChem (6604221) PubChem (124226124) PubChem (124518166) PubChem (124604978) PubChem (124605145) PubChem (124605175) PubChem (124723146) PubChem (124798369) PubChem (124762348) PubChem (124822557) PubChem (9833120) PubChem (10032882) PubChem (129009922) PubChem (129125718) PubChem (129445574) PubChem (129445576) PubChem (129666958) PubChem (10897911) PubChem (132274086) PubChem (133126690) PubChem (133126790) PubChem (133550114) PubChem (133688268) PubChem (134081643) PubChem (134081274) PubChem (134693955) PubChem (118725304) PubChem (11970254) PubChem (124226125) PubChem (124523502) PubChem (124604979) PubChem (124605144) PubChem (124605146) PubChem (124716782) PubChem (124716783) PubChem (124723147) PubChem (124762349) PubChem (12358519) PubChem (12358515) PubChem (12358508) PubChem (124822555) PubChem (124822558) PubChem (124870987) PubChem (137705094) PubChem (126969058) PubChem (129010384) PubChem (129119817) PubChem (129445575) PubChem (139247122) PubChem (129627840) PubChem (129628729) PubChem (131665174) PubChem (141945645) PubChem (133562871) PubChem (133602826) PubChem (146158524) PubChem (134081264) PubChem (134693174) PubChem (135026875) PubChem (157254288) PubChem (163003493) PubChem (163003495) PubChem (138113460) PubChem (138403276) PubChem (165844830) PubChem (140886742) PubChem (141646830) PubChem (145774355) PubChem (169440260) PubChem (155899868) PubChem (155900413) PubChem (172897573) PubChem (161123720) PubChem (163003494) PubChem (163003496) PubChem (166604455) PubChem (166639762) PubChem (169289157) PubChem (171114703) PubChem (172897571) PubChem (16212992) PubChem (16213052) | |||
| 3 | D, F (A, B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (3084486) PubChem (60098857) PubChem (57448939) PubChem (6101632) PubChem (6604175) PubChem (91746160) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (11811538) PubChem (93088131) PubChem (93630083) PubChem (12049241) | |||
| 4 | G (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 604 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 414 (UniProt: Q3HTL6)
| PDB | External Database | Details |
|---|---|---|
| Pro 54 | Ala 55 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90784.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2300.5 | |
| All* | Total formula weight | 93084.5 |
