2IYF
The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | OLEANDOMYCIN GLYCOSYLTRANSFERASE | polymer | 415 | 45392.0 | 2 | UniProt (Q3HTL6) Pfam (PF06722) UniProt (by SIFTS) (Q53685) | STREPTOMYCES ANTIBIOTICUS | OLED |
| 2 | C, E (A, B) | ERYTHROMYCIN A | non-polymer | 733.9 | 2 | Chemie (ERY) | |||
| 3 | D, F (A, B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
| 4 | G (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 604 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 414 (UniProt: Q3HTL6)
| PDB | External Database | Details |
|---|---|---|
| Pro 54 | Ala 55 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90784.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2300.5 | |
| All* | Total formula weight | 93084.5 |
