2IXE

Crystal structure of the ATPase domain of TAP1 with ATP (D645N mutant)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, D)	ANTIGEN PEPTIDE TRANSPORTER 1	polymer	271	29482.4	2	UniProt (P36370) Pfam (PF00005)	RATTUS NORVEGICUS (RAT)	TAP1, APT1, PEPTIDE TRANSPORTER TAP1, ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 2
2	C, F (A, D)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
3	D, G (A, D)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	E (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5	H, I (A, D)	water	water		18.0	332	Chemie (HOH)

Sequence modifications

A, D: 465 - 725 (UniProt: P36370)

PDB	External Database	Details
Met 464	-	expression tag
Ala 726	-	expression tag
Ala 727	-	expression tag
Ala 728	-	expression tag
His 729	-	expression tag
His 730	-	expression tag
His 731	-	expression tag
His 732	-	expression tag
His 733	-	expression tag
His 734	-	expression tag
Asn 645	Asp 645	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58964.9
Non-Polymers*	Number of molecules	5
	Total formula weight	1157.9
All*	Total formula weight	60122.8

*Water molecules are not included.