2IXE

Crystal structure of the ATPase domain of TAP1 with ATP (D645N mutant)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0016887	molecular_function	ATP hydrolysis activity
D	0005524	molecular_function	ATP binding
D	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 2

Chain	Residue
A	ATP1
A	SER522
A	HOH2003
A	HOH2036
A	HOH2114

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 A 3

Chain	Residue
A	LYS481
A	HOH2005
A	HOH2008

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 2

Chain	Residue
D	SER522
D	HOH2001
D	HOH2002
D	HOH2007
D	ATP1

---

site_id	AC4
Number of Residues	22
Details	BINDING SITE FOR RESIDUE ATP A 1

Chain	Residue
A	MG2
A	TYR489
A	VAL497
A	ASN517
A	GLY518
A	SER519
A	GLY520
A	LYS521
A	SER522
A	THR523
A	GLN678
A	HOH2001
A	HOH2002
A	HOH2003
A	HOH2004
A	HOH2114
D	GLN619
D	SER621
D	GLY622
D	GLY623
D	GLN624
D	HOH2118

---

site_id	AC5
Number of Residues	27
Details	BINDING SITE FOR RESIDUE ATP D 1

Chain	Residue
A	GLN619
A	SER621
A	GLY622
A	GLY623
A	GLN624
A	HOH2104
D	MG2
D	TYR489
D	HIS492
D	VAL497
D	ASN517
D	GLY518
D	SER519
D	GLY520
D	LYS521
D	SER522
D	THR523
D	GLN678
D	HOH2001
D	HOH2002
D	HOH2003
D	HOH2004
D	HOH2005
D	HOH2006
D	HOH2007
D	HOH2008
D	HOH2009

---

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQRQAVALARAL

Chain	Residue	Details
A	LEU620-LEU634

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00434, ECO:0000269|PubMed:17018292, ECO:0007744|PDB:2IXE, ECO:0007744|PDB:2IXF, ECO:0007744|PDB:2IXG, ECO:0007744|PDB:4K8O

Chain	Residue	Details
A	GLY515
D	GLY515

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:17018292, ECO:0000269|PubMed:25377891, ECO:0007744|PDB:2IXE, ECO:0007744|PDB:2IXF, ECO:0007744|PDB:4K8O

Chain	Residue	Details
A	SER522
A	ASN618
D	SER522
D	ASN618

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:17018292, ECO:0000269|PubMed:25377891, ECO:0007744|PDB:2IXE, ECO:0007744|PDB:2IXG, ECO:0007744|PDB:4K8O

Chain	Residue	Details
A	GLN678
D	GLN678

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