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2IPH

X-ray Structure at 1.75 A Resolution of a Norovirus Protease Linked to an Active Site Directed Peptide Inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Thiol protease P3Cpolymer18119305.32UniProt (Q04544)Southampton virus (serotype 3)3C-like protease, 3C-pro
2C, D
(A, B)
N-ACETYL-L-ALPHA-GLUTAMYL-L-PHENYLALANYL-L-GLUTAMINYL-N-[(1S)-4-AMINO-1-(2-CARBOXYETHYL)-4-OXOBUTYL]-L-LEUCINAMIDEnon-polymer733.82Chemie (LGG)
3E, F
(A, B)
waterwater18.0247Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight38610.5
Non-Polymers*Number of molecules2
Total formula weight1467.6
All*Total formula weight40078.2
*Water molecules are not included.

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PDB entries from 2025-07-23

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