2IO4
Crystal structure of PCNA12 dimer from Sulfolobus solfataricus.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | DNA polymerase sliding clamp B | polymer | 249 | 27521.7 | 2 | UniProt (P57766) Pfam (PF00705) | Sulfolobus solfataricus | Proliferating cell nuclear antigen homolog B, PCNA B |
| 2 | B, D (B, D) | DNA polymerase sliding clamp C | polymer | 246 | 27592.3 | 2 | UniProt (Q97Z84) Pfam (PF00705) Pfam (PF02747) | Sulfolobus solfataricus | Proliferating cell nuclear antigen homolog C, PCNA C |
| 3 | E, G, H, I, J (A, B) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 5 | Chemie (MPD) | |||
| 4 | F (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 249 (UniProt: P57766)
B, D: 2 - 246 (UniProt: Q97Z84)
| PDB | External Database | Details |
|---|---|---|
| Val 2 | Phe 2 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 110227.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 630.9 | |
| All* | Total formula weight | 110858.9 |
