2IO4
Crystal structure of PCNA12 dimer from Sulfolobus solfataricus.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0006260 | biological_process | DNA replication |
| A | 0006272 | biological_process | leading strand elongation |
| A | 0006275 | biological_process | regulation of DNA replication |
| A | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0006260 | biological_process | DNA replication |
| B | 0006272 | biological_process | leading strand elongation |
| B | 0006275 | biological_process | regulation of DNA replication |
| B | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| C | 0003677 | molecular_function | DNA binding |
| C | 0006260 | biological_process | DNA replication |
| C | 0006272 | biological_process | leading strand elongation |
| C | 0006275 | biological_process | regulation of DNA replication |
| C | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| D | 0003677 | molecular_function | DNA binding |
| D | 0006260 | biological_process | DNA replication |
| D | 0006272 | biological_process | leading strand elongation |
| D | 0006275 | biological_process | regulation of DNA replication |
| D | 0030337 | molecular_function | DNA polymerase processivity factor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 701 |
| Chain | Residue |
| B | ASP145 |
| B | ASP149 |
| D | ASP145 |
| D | ASP149 |
| D | HOH266 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MPD A 250 |
| Chain | Residue |
| A | LYS44 |
| A | PRO228 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD B 301 |
| Chain | Residue |
| B | GLU146 |
| B | HOH751 |
| B | HOH752 |
| D | GLU146 |
| B | ASP142 |
| B | ASP145 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD B 401 |
| Chain | Residue |
| B | ASP21 |
| B | ASN204 |
| B | LYS207 |
| D | ASP21 |
| D | GLU200 |
| D | ASN204 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MPD B 501 |
| Chain | Residue |
| B | ARG44 |
| B | TYR240 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MPD B 601 |
| Chain | Residue |
| B | GLY151 |
| B | GLU152 |
| B | ILE168 |
| B | GLY169 |
| B | ASP170 |
| B | HOH712 |
| D | ARG210 |
Functional Information from PROSITE/UniProt
| site_id | PS01251 |
| Number of Residues | 24 |
| Details | PCNA_1 Proliferating cell nuclear antigen signature 1. GIrVsGIDpSRVvFLdIfLpssyF |
| Chain | Residue | Details |
| B | GLY34-PHE57 |
