2IM3
Crystal structure of poliovirus polymerase complexed with UTP and Mn2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | poliovirus polymerase | polymer | 461 | 52987.9 | 1 | UniProt (P03300) Pfam (PF00680) | Human poliovirus 1 | |
| 2 | B, C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 4 | E (A) | URIDINE 5'-TRIPHOSPHATE | non-polymer | 484.1 | 1 | Chemie (UTP) | |||
| 5 | F, G, H, I (A) | ACETIC ACID | non-polymer | 60.1 | 4 | Chemie (ACY) | |||
| 6 | J (A) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A: 1 - 461 (UniProt: P03300)
| PDB | External Database | Details |
|---|---|---|
| Cas 96 | Cys 1843 | modified residue |
| Cas 212 | Cys 1959 | modified residue |
| Cas 281 | Cys 2028 | modified residue |
| Cas 290 | Cys 2037 | modified residue |
| Asp 446 | Leu 2193 | engineered mutation |
| Asp 455 | Arg 2202 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52987.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 857.2 | |
| All* | Total formula weight | 53845.1 |
