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2IC5

Crystal structure of human RAC3 grown in the presence of Gpp(NH)p.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Ras-related C3 botulinum toxin substrate 3polymer18019992.02UniProt (P60763)
Pfam (PF00071)
Homo sapiens (human)p21-Rac3
2C, G
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
3D, H
(A, B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
4E
(A)
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.21Chemie (GNP)
5F
(A)
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer209.21Chemie (BTB)
6I
(B)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
7J, K
(A, B)
waterwater18.0278Chemie (HOH)
Sequence modifications
A, B: 1 - 178 (UniProt: P60763)
PDBExternal DatabaseDetails
Ser 0-cloning artifact
Gly 178Cys 178engineered mutation
Gly 179-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight39984.0
Non-Polymers*Number of molecules7
Total formula weight1294.2
All*Total formula weight41278.1
*Water molecules are not included.

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PDB entries from 2026-02-11

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