2I0B
Crystal structure of the GluR6 ligand binding core ELKQ mutant dimer at 1.96 Angstroms Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Glutamate receptor, ionotropic kainate 2 | polymer | 259 | 29371.6 | 3 | UniProt (P42260) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | Glutamate receptor 6, GluR-6, GluR6 |
| 2 | D, F, G (A, B, C) | GLUTAMIC ACID | non-polymer | 147.1 | 3 | Chemie (GLU) | |||
| 3 | E (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | H, I, J (A, B, C) | water | water | 18.0 | 538 | Chemie (HOH) |
Sequence modifications
A, B, C: 2 - 117 (UniProt: P42260)
A, B, C: 120 - 259 (UniProt: P42260)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Glu 98 | Lys 525 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| Leu 233 | Ile 780 | engineered mutation |
| Lys 237 | Gln 784 | engineered mutation |
| Gln 241 | Glu 788 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 88114.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 537.4 | |
| All* | Total formula weight | 88652.3 |
