2I0B
Crystal structure of the GluR6 ligand binding core ELKQ mutant dimer at 1.96 Angstroms Resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| C | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| C | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE SO4 B 601 |
| Chain | Residue |
| B | PHE102 |
| C | ARG228 |
| C | THR232 |
| C | HOH308 |
| C | HOH335 |
| B | LYS104 |
| B | ARG228 |
| B | ASP229 |
| B | THR232 |
| B | HOH701 |
| C | GLU97 |
| C | PHE102 |
| C | LYS104 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU A 301 |
| Chain | Residue |
| A | TYR61 |
| A | PRO89 |
| A | LEU90 |
| A | ALA91 |
| A | ARG96 |
| A | GLY141 |
| A | ALA142 |
| A | THR143 |
| A | GLU191 |
| A | HOH305 |
| A | HOH311 |
| A | HOH318 |
| A | HOH330 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU B 302 |
| Chain | Residue |
| B | TYR61 |
| B | PRO89 |
| B | LEU90 |
| B | ALA91 |
| B | ARG96 |
| B | GLY141 |
| B | ALA142 |
| B | THR143 |
| B | GLU191 |
| B | HOH605 |
| B | HOH619 |
| B | HOH650 |
| B | HOH672 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GLU C 303 |
| Chain | Residue |
| C | TYR61 |
| C | PRO89 |
| C | LEU90 |
| C | ALA91 |
| C | ARG96 |
| C | GLY141 |
| C | ALA142 |
| C | THR143 |
| C | GLU191 |
| C | HOH311 |
| C | HOH313 |
| C | HOH337 |
| C | HOH357 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15721240","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17115050","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778115","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39592599","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1S50","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S7Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I0B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I0C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B36","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B38","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B39","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9DXQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9DXR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9DXS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9DXT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15677325","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8163463","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
