2HZP
Crystal Structure of Homo Sapiens Kynureninase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kynureninase | polymer | 501 | 56575.9 | 1 | UniProt (Q16719) Pfam (PF22580) | Homo sapiens (human) | L-kynurenine hydrolase |
| 2 | B (A) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 3 | C (A) | water | water | 18.0 | 540 | Chemie (HOH) |
Sequence modifications
A: 1 - 465 (UniProt: Q16719)
| PDB | External Database | Details |
|---|---|---|
| Met -35 | - | cloning artifact |
| Arg -34 | - | cloning artifact |
| Gly -33 | - | cloning artifact |
| Ser -32 | - | cloning artifact |
| His -31 | - | expression tag |
| His -30 | - | expression tag |
| His -29 | - | expression tag |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| Gly -25 | - | cloning artifact |
| Met -24 | - | cloning artifact |
| Ala -23 | - | cloning artifact |
| Ser -22 | - | cloning artifact |
| Met -21 | - | cloning artifact |
| Thr -20 | - | cloning artifact |
| Gly -19 | - | cloning artifact |
| Gly -18 | - | cloning artifact |
| Gln -17 | - | cloning artifact |
| Gln -16 | - | cloning artifact |
| Met -15 | - | cloning artifact |
| Gly -14 | - | cloning artifact |
| Arg -13 | - | cloning artifact |
| Asp -12 | - | cloning artifact |
| Leu -11 | - | cloning artifact |
| Tyr -10 | - | cloning artifact |
| Asp -9 | - | cloning artifact |
| Asp -8 | - | cloning artifact |
| Asp -7 | - | cloning artifact |
| Asp -6 | - | cloning artifact |
| Lys -5 | - | cloning artifact |
| Asp -4 | - | cloning artifact |
| His -3 | - | cloning artifact |
| Pro -2 | - | cloning artifact |
| Phe -1 | - | cloning artifact |
| Thr 0 | - | cloning artifact |
| Csx 45 | Cys 45 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 56575.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 247.1 | |
| All* | Total formula weight | 56823.1 |
