2HVY
Crystal structure of an H/ACA box RNP from Pyrococcus furiosus
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | E | H/ACA RNA | polymer | 65 | 21021.5 | 1 | |||
2 | A | Probable tRNA pseudouridine synthase B | polymer | 346 | 39453.9 | 1 | UniProt (Q7LWY0) Pfam (PF08068) Pfam (PF01509) Pfam (PF16198) Pfam (PF01472) In PDB | Pyrococcus furiosus | tRNA pseudouridine 55 synthase, Psi55 synthase, tRNA-uridine isomerase, tRNA pseudouridylate synthase |
3 | B | Small nucleolar rnp similar to gar1 | polymer | 104 | 12340.8 | 1 | UniProt (Q8U029) Pfam (PF04410) In PDB | Pyrococcus furiosus | Gar1 |
4 | C | Ribosome biogenesis protein Nop10 | polymer | 60 | 7214.6 | 1 | UniProt (Q8U1R4) Pfam (PF04135) In PDB | Pyrococcus furiosus | Nop10 |
5 | D | 50S ribosomal protein L7Ae | polymer | 130 | 14314.6 | 1 | UniProt (Q8U160) Pfam (PF01248) In PDB | Pyrococcus furiosus | L7ae |
6 | A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
7 | C | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
8 | water | water | 18.0 | 118 | Chemie (HOH) |
Sequence modifications
A: 4 - 343 (UniProt: Q7LWY0)
C: 1 - 60 (UniProt: Q8U1R4)
D: 2 - 124 (UniProt: Q8U160)
PDB | External Database | Details |
---|---|---|
His 344 | - | expression tag |
His 345 | - | expression tag |
His 346 | - | expression tag |
His 347 | - | expression tag |
His 348 | - | expression tag |
His 349 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Lys 2 | Arg 2 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Ala 2 | Met 1 | engineered mutation |
His 125 | - | expression tag |
His 126 | - | expression tag |
His 127 | - | expression tag |
His 128 | - | expression tag |
His 129 | - | expression tag |
His 130 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 94345.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 572.6 | |
All* | Total formula weight | 94918.0 |