2HVY

Crystal structure of an H/ACA box RNP from Pyrococcus furiosus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000495	biological_process	box H/ACA sno(s)RNA 3'-end processing
A	0001522	biological_process	pseudouridine synthesis
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0006396	biological_process	RNA processing
A	0008033	biological_process	tRNA processing
A	0009451	biological_process	RNA modification
A	0009982	molecular_function	pseudouridine synthase activity
A	0016853	molecular_function	isomerase activity
A	0031118	biological_process	rRNA pseudouridine synthesis
A	0031119	biological_process	tRNA pseudouridine synthesis
A	0031120	biological_process	snRNA pseudouridine synthesis
A	0106029	molecular_function	tRNA pseudouridine synthase activity
A	1990481	biological_process	mRNA pseudouridine synthesis
B	0001522	biological_process	pseudouridine synthesis
B	0042254	biological_process	ribosome biogenesis
C	0001522	biological_process	pseudouridine synthesis
C	0005515	molecular_function	protein binding
C	0006364	biological_process	rRNA processing
C	0030515	molecular_function	snoRNA binding
C	0031118	biological_process	rRNA pseudouridine synthesis
C	0031120	biological_process	snRNA pseudouridine synthesis
C	0042254	biological_process	ribosome biogenesis
C	0070034	molecular_function	telomerase RNA binding
C	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
C	1990904	cellular_component	ribonucleoprotein complex
D	0001682	biological_process	tRNA 5'-leader removal
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0004526	molecular_function	ribonuclease P activity
D	0005737	cellular_component	cytoplasm
D	0005840	cellular_component	ribosome
D	0006364	biological_process	rRNA processing
D	0006412	biological_process	translation
D	0008033	biological_process	tRNA processing
D	0019843	molecular_function	rRNA binding
D	0022627	cellular_component	cytosolic small ribosomal subunit
D	0042254	biological_process	ribosome biogenesis
D	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 201

Chain	Residue
C	CYS8
C	CYS11
C	CYS20
C	CYS23

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ATP A 501

Chain	Residue
E	C8
E	C9
E	G49
E	G50
A	HIS118
A	HIS120
A	ARG169
A	HIS199
B	LYS12

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Functional Information from PROSITE/UniProt

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CeekeIPYiyVpSKkeLG

Chain	Residue	Details
D	CYS71-GLY88

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_01081

Chain	Residue	Details
A	ASP85

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