2HVR

Structure of T4 RNA Ligase 2 with Nicked 5'-Adenylated nucleic acid duplex containing a 3'-deoxyribonucleotide at the nick

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (C, F)	5'-D(*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*TP*TP*G)-3'	polymer	24	7440.8	2
2	B, E (D, G)	5'-D(*CP*AP*AP*TP*TP*GP*CP*GP*AP*C)-R(P*(OMC)P*C)-3'	polymer	12	3637.4	2
3	C, F (E, H)	5'-R(P*A)-D(P*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*T)-3'	polymer	13	3975.6	2
4	G, H (A, B)	T4 RNA ligase 2	polymer	335	37714.2	2	UniProt (P32277) Pfam (PF09414) Pfam (PF18043)	Enterobacteria phage T4
5	I, J, K (C, F, A)	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	3	Chemie (BTB)
6	L, M, N, O, P... (C, F, G, H, A...)	water	water		18.0	129	Chemie (HOH)

Sequence modifications

A, B: 1 - 334 (UniProt: P32277)

PDB	External Database	Details
Ser 0	-	cloning artifact
Gly 112	Cys 112	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	105535.9
Non-Polymers*	Number of molecules	3
	Total formula weight	627.7
All*	Total formula weight	106163.7

*Water molecules are not included.