2HV8
Crystal structure of GTP-bound Rab11 in complex with FIP3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Ras-related protein Rab-11A | polymer | 172 | 19353.8 | 3 | UniProt (P62491) Pfam (PF00071) In PDB | Homo sapiens (human) | Rab-11, YL8 |
| 2 | D, E, F | Rab11 family-interacting protein 3 | polymer | 64 | 7127.0 | 3 | UniProt (O75154) Pfam (PF09457) In PDB | Homo sapiens (human) | Rab11-FIP3, EF hands-containing Rab-interacting protein, Eferin |
| 3 | A, B, C | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | A, B, C | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | A, B, C | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 3 | Chemie (GTP) | |||
| 6 | B | METHOXYETHANE | non-polymer | 60.1 | 1 | Chemie (2ME) | |||
| 7 | B | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 8 | water | water | 18.0 | 906 | Chemie (HOH) |
Sequence modifications
A, B, C: 6 - 175 (UniProt: P62491)
D, E, F: 695 - 756 (UniProt: O75154)
| PDB | External Database | Details |
|---|---|---|
| Gly 4 | - | cloning artifact |
| Ser 5 | - | cloning artifact |
| Leu 70 | Gln 69 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 693 | - | cloning artifact |
| Ser 694 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 79442.4 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2378.1 | |
| All* | Total formula weight | 81820.5 |
