2HUE
Structure of the H3-H4 chaperone Asf1 bound to histones H3 and H4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Anti-silencing protein 1 | polymer | 175 | 19664.0 | 1 | UniProt (P32447) Pfam (PF04729) | Saccharomyces cerevisiae (baker's yeast) | |
| 2 | B (B) | Histone H3 | polymer | 77 | 8888.5 | 1 | UniProt (Q92133) Pfam (PF00125) UniProt (by SIFTS) (P84233) | Xenopus laevis (African clawed frog) | |
| 3 | C (C) | Histone H4 | polymer | 84 | 9540.3 | 1 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E, H (A, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | F, G (B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 7 | I, J, K (A, B, C) | water | water | 18.0 | 367 | Chemie (HOH) |
Sequence modifications
A: 2 - 169 (UniProt: P32447)
B: 61 - 135 (UniProt: Q92133)
C: 20 - 102 (UniProt: P62799)
| PDB | External Database | Details |
|---|---|---|
| Pro -5 | - | cloning artifact |
| Leu -4 | - | cloning artifact |
| Gly -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| Pro -1 | - | cloning artifact |
| Asn 0 | - | cloning artifact |
| Ser 1 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Met 59 | - | initiating methionine |
| Ala 60 | - | cloning artifact |
| Ala 102 | Gly 103 | engineered mutation |
| Ala 111 | Gly 112 | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 38092.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 441.7 | |
| All* | Total formula weight | 38534.4 |
