2HKJ

Topoisomerase VI-B bound to radicicol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Type II DNA topoisomerase VI subunit B	polymer	469	53510.4	1	UniProt (O05207)	Sulfolobus shibatae	TopoVI-B
2	B (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
3	C (A)	DIMETHYL SULFOXIDE	non-polymer		78.1	1	Chemie (DMS) PubChem (679)
4	D (A)	RADICICOL	non-polymer		364.8	1	Chemie (RDC) PubChem (5033) PubChem (23304243) PubChem (23351218) PubChem (23375462) PubChem (24871113) PubChem (24883610) PubChem (44323216) PubChem (44634642) PubChem (51535441) PubChem (52224359) PubChem (52224360) PubChem (56846487) PubChem (57685060) PubChem (57729285) PubChem (59114079) PubChem (45933581) PubChem (60028429) PubChem (60043244) PubChem (60046279) PubChem (155901071) PubChem (71684643) PubChem (509980) PubChem (90798921) PubChem (89174685) PubChem (91150137) PubChem (91414470) PubChem (91421888) PubChem (91499444) PubChem (5289273) PubChem (5311380) PubChem (5353918) PubChem (5359013) PubChem (98043729) PubChem (92265824) PubChem (6323491) PubChem (92966529) PubChem (98043730) PubChem (9799192) PubChem (9863893) PubChem (123740891) PubChem (10915493) PubChem (11268547) PubChem (124918602) PubChem (134688667) PubChem (135121972) PubChem (137433107) PubChem (142109646) PubChem (152743492) PubChem (163001975) PubChem (163001976) PubChem (173786049) PubChem (16196977)
5	E (A)	water	water		18.0	355	Chemie (HOH)

Sequence modifications

A: 2 - 470 (UniProt: O05207)

PDB	External Database	Details
Tyr 303	Asp 303	SEE REMARK 999
Asp 435	Asn 435	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	53510.4
Non-Polymers*	Number of molecules	3
	Total formula weight	467.2
All*	Total formula weight	53977.6

*Water molecules are not included.