2HI4
Crystal Structure of Human Microsomal P450 1A2 in complex with alpha-naphthoflavone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cytochrome P450 1A2 | polymer | 495 | 56293.6 | 1 | UniProt (P05177) Pfam (PF00067) In PDB | Homo sapiens (human) | CYPIA2, P450-P3, P3, 450, P450 4 |
| 2 | A | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | A | 2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | non-polymer | 272.3 | 1 | Chemie (BHF) | |||
| 4 | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A: 27 - 515 (UniProt: P05177)
| PDB | External Database | Details |
|---|---|---|
| Met 25 | - | cloning artifact |
| Ala 26 | - | cloning artifact |
| His 516 | - | expression tag |
| His 517 | - | expression tag |
| His 518 | - | expression tag |
| His 519 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 56293.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 888.8 | |
| All* | Total formula weight | 57182.4 |
