2HEV
Crystal structure of the complex between OX40L and OX40
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (F) | Tumor necrosis factor ligand superfamily member 4 | polymer | 137 | 15858.0 | 1 | UniProt (P23510) | Homo sapiens (human) | OX40 ligand, OX40L, Glycoprotein Gp34, TAX transcriptionally-activated glycoprotein 1, CD252 antigen |
| 2 | B (R) | Tumor necrosis factor receptor superfamily member 4 | polymer | 146 | 15808.8 | 1 | UniProt (P43489) Pfam (PF00020) | Homo sapiens (human) | OX40L receptor, ACT35 antigen, TAX transcriptionally-activated glycoprotein 1 receptor, CD134 antigen |
| 3 | C, D (F, R) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | E, F (F, R) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
F: 51 - 183 (UniProt: P23510)
R: 29 - 170 (UniProt: P43489)
| PDB | External Database | Details |
|---|---|---|
| Gly 47 | - | cloning artifact |
| Ser 48 | - | cloning artifact |
| His 49 | - | cloning artifact |
| Met 50 | - | cloning artifact |
| Asp 90 | Asn 90 | engineered mutation |
| Asp 114 | Asn 114 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | cloning artifact |
| Ser 26 | - | cloning artifact |
| His 27 | - | cloning artifact |
| Met 28 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31666.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 32109.2 |
