2HEV

Crystal structure of the complex between OX40L and OX40

Functional Information from GO Data

Chain	GOid	namespace	contents
F	0005125	molecular_function	cytokine activity
F	0005164	molecular_function	tumor necrosis factor receptor binding
F	0006955	biological_process	immune response
F	0016020	cellular_component	membrane
R	0005031	molecular_function	tumor necrosis factor receptor activity
R	0006954	biological_process	inflammatory response

Functional Information from PROSITE/UniProt

site_id	PS00251
Number of Residues	17
Details	THD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. ViINcDGFYLIslKGyF

Chain	Residue	Details
F	VAL93-PHE109

---

site_id	PS00652
Number of Residues	34
Details	TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Cvgdt..Ypsndr.....C..Che.Crpgngmvsr..Csrsq..NTVC

Chain	Residue	Details
R	CYS31-CYS64
R	CYS64-CYS107

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16905106","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	35
Details	Repeat: {"description":"TNFR-Cys 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	41
Details	Repeat: {"description":"TNFR-Cys 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	18
Details	Repeat: {"description":"TNFR-Cys 3; truncated"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	40
Details	Repeat: {"description":"TNFR-Cys 4"}

Chain

Residue

Details

---