2HC2
Engineered protein tyrosine phosphatase beta catalytic domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Receptor-type tyrosine-protein phosphatase beta | polymer | 291 | 33780.3 | 1 | UniProt (P23467) Pfam (PF00102) | Homo sapiens (human) | Protein-tyrosine phosphatase beta, R-PTP-beta |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C, D (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | E (A) | water | water | 18.0 | 303 | Chemie (HOH) |
Sequence modifications
A: 1676 - 1965 (UniProt: P23467)
| PDB | External Database | Details |
|---|---|---|
| Ser 1675 | - | cloning artifact |
| - | Asn 1748 | deletion |
| - | Val 1749 | deletion |
| - | Asp 1750 | deletion |
| - | Asp 1751 | deletion |
| - | Asp 1752 | deletion |
| Gly 1748 | Pro 1753 | engineered mutation |
| Gly 1749 | Cys 1754 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33780.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 70.3 | |
| All* | Total formula weight | 33850.6 |
