2HAP

STRUCTURE OF A HAP1-18/DNA COMPLEX REVEALS THAT PROTEIN/DNA INTERACTIONS CAN HAVE DIRECT ALLOSTERIC EFFECTS ON TRANSCRIPTIONAL ACTIVATION

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA (5'-D(*AP*CP*GP*CP*TP*AP*TP*TP*AP*TP*CP*GP*CP*TP*AP*TP*TP*AP*GP*T)-3')	polymer	20	6099.0	1			UAS CYC7
2	B (B)	DNA (5'-D(*AP*CP*TP*AP*AP*TP*AP*GP*CP*GP*AP*TP*AP*AP*TP*AP*GP*CP*GP*T)-3')	polymer	20	6166.0	1			UAS CYC7
3	C, D (C, D)	PROTEIN (HEME ACTIVATOR PROTEIN)	polymer	81	9696.5	2	UniProt (P12351) Pfam (PF00172) UniProt (by SIFTS) (P0CS82)	Saccharomyces cerevisiae (baker's yeast)	HAP1.18
4	E, F, G, H, I (C, D)	ZINC ION	non-polymer		65.4	5	Chemie (ZN)
5	J, K, L, M (A, B, C, D)	water	water		18.0	74	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	31658.0
Non-Polymers*	Number of molecules	5
	Total formula weight	327.0
All*	Total formula weight	31985.1

*Water molecules are not included.