2HA7
Crystal structure of mutant S203A of mouse acetylcholinesterase complexed with butyrylthiocholine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acetylcholinesterase | polymer | 543 | 59748.5 | 2 | UniProt (P21836) Pfam (PF00135) | Mus musculus (house mouse) | AChE |
| 2 | C, D, E, F, L... (A, B) | IODIDE ION | non-polymer | 126.9 | 9 | Chemie (IOD) | |||
| 3 | G, Q (A, B) | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL | non-polymer | 120.2 | 2 | Chemie (ETM) | |||
| 4 | H, R (A, B) | butanoic acid | non-polymer | 88.1 | 2 | Chemie (BUA) | |||
| 5 | I, J (A) | 2-(BUTYRYLSULFANYL)-N,N,N-TRIMETHYLETHANAMINIUM | non-polymer | 190.3 | 2 | Chemie (BCH) | |||
| 6 | K (A) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 7 | S, T (A, B) | water | water | 18.0 | 234 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 543 (UniProt: P21836)
| PDB | External Database | Details |
|---|---|---|
| Ala 203 | Ser 234 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 119497.0 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2221.8 | |
| All* | Total formula weight | 121718.8 |
